Sample Nursing Research Paper on Acute Inflammation

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Inflammation occurs as a response of the immune system to harmful stimuli. The occurrence of acute stimuli can be exhibited in hours, minutes, or even seconds (Weber et al., 2015). In most cases, acute inflammation is a result of an injury to the tissues that can occur due to an activation of the immune responses or physical harm to the tissues.

Underlying Principles

The occurrence of acute inflammation is exhibited in three different changes within the skin and the body. The first is increased blood flow since the blood vessels within the affected area have been dilated. The second change is increased permeability, which is majorly seen on the capillaries. Lastly, there is migration of the neutrophils and in some cases macrophages from the capillaries into the interstitial space.

Nursing Interventions

Acute inflammation is experienced within a short time; therefore, treatment can either be initiated by the body or through taking medication to ease the discomfort and pain. One option is using the NSAIDs (Non-Steroidal Inflammatory Drugs) such as aspirin and ibuprofen that work on the enzymes triggering the inflammation on the body (Puranik et al., 2016). Patients can also be prescribed narcotics that are used to manage severe pain. Examples of narcotics include tramadol, morphine, or codeine. However, the administration of narcotics is minimized to reduce possible cases of addiction or over-dependence. Alternative forms of treatment are also encouraged in different settings such as the use of an ice pack. In other cases, patients are encouraged to drink lots of water to help increase the healing process. For cases of recurrence symptoms, nurses have to consider providing an alternative change to the diets a patient is taking. Other forms of inflammation is due to poor diet balance; solutions could be the use of oregano, cloves, nutmeg, or even cinnamon.


Works Cited

Puranik, Rajesh; Bao, Shisan; Bonin, Antonio; Kaur, Ravinder; Weder, Jane E.; Casbolt, Llewellyn; Hambley, Trrevor; Lay, Peter,… Rye, Kerry-Anne (2016). A novel class of copper (II)-and zinc (II)-bound non-steroidal anti-inflammatory drugs that inhibits acute inflammation in vivo. Cell & bioscience, 6(1), 9. doi:10.1186/s13578-016-0076-8. Retrieved from:

Weber, Georg F.; Chousterman, Benjamin G.; He, Shun; Fenn, Ashley M.; Nairz, Manfred; Anzai, Atsushi, . . . Noiret, Lorette. (2015). Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis. Science, 347(6227), 1260-1265. doi:10.1126/science.aaa4268. Retrieved from: